Pleural Fibrosis |
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Pleural fibrosis is the development of fibrous tissue in the pleura. It may be localized or widespread, and may vary in thickness from a slight milky discoloration to a thick, white peel that encases one or both lungs. The fibrous tissue usually contains asbestos bodies and fibers, as do the underlying lungs. Pleural fibrosis develops 15+ years after asbestos exposure (usually amphiboles), which is typically short but heavy. Time since first exposure is the important association, rather than cumulative exposure.
Pleural fibrosis is often diagnosed by chance on chest x-ray. However, some patients present with breathlessness, chest pain or both. Pleural fibrosis is associated with a reduction in lung function, but this often produces few symptoms, even when the chest x-ray indicates widespread fibrosis. Occasionally, the fibrosis may become so severe that it restricts the lungs ability to breathe; pleurectomy may be indicated in these cases.
There is evidence that people who develop pleural fibrosis are more likely to later develop fibrosis of the lungs (asbestosis).
